POSICAINE
Is a prescription local anesthetic used primarily in dental procedures for adults and children aged 4 years and older. Manufactured by Novocol Pharmaceutical of Canada Inc., it temporarily blocks painful nerve conduction in the mouth during dental surgeries, fillings, or extractions.
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Active Ingredients & Strength
- Articaine Hydrochloride (4%): An amide-type local anesthetic that prevents sodium ion influx during nerve action potentials, stopping the transmission of pain signals.
- Epinephrine (1:100,000): A vasoconstrictor added to narrow local blood vessels. It slows the entry of the anesthetic into general circulation, prolongs the numbing effect, and controls minor surgical bleeding.
Key Clinical Properties
- Onset of Action: Very rapid, typically taking 1 to 3 minutes to numb the target area after injection.
- Duration: Provides clinical anesthesia lasting up to 75 minutes per cartridge.
- Administration Routes: Delivered by dental professionals through intraoral submucosal infiltration or local nerve blocks.
- Elimination Half-Life: Extremely short at approximately 25 minutes, meaning the body breaks it down and eliminates it quickly.
- Articaine Hydrochloride (4%): An amide-type local anesthetic that prevents sodium ion influx during nerve action potentials, stopping the transmission of pain signals.
- Epinephrine (1:100,000): A vasoconstrictor added to narrow local blood vessels. It slows the entry of the anesthetic into general circulation, prolongs the numbing effect, and controls minor surgical bleeding.
Key Clinical Properties
- Onset of Action: Very rapid, typically taking 1 to 3 minutes to numb the target area after injection.
- Duration: Provides clinical anesthesia lasting up to 75 minutes per cartridge.
- Administration Routes: Delivered by dental professionals through intraoral submucosal infiltration or local nerve blocks.
- Elimination Half-Life: Extremely short at approximately 25 minutes, meaning the body breaks it down and eliminates it quickly.